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Generic Name: disulfiram (dye SUL fi ram brand Names: Antabuse, medically reviewed on March 13, 2018. Antabuse (disulfiram) blocks an enzyme that is involved in metabolizing alcohol intake. Disulfiram produces very unpleasant side effects when combined with alcohol in the body. Antabuse is used in certain people with chronic alcoholism. This medicine can help keep you antabuse treatment for alcoholism from drinking because of the unpleasant side effects that will occur if you antabuse treatment for alcoholism consume alcohol while taking Antabuse. Antabuse is used together with behavior modification, psychotherapy, and counseling support to help you stop drinking. This medicine is not a cure for alcoholism. Important information, you should not use Antabuse if you have recently taken metronidazole antabuse treatment for alcoholism or paraldehyde, or if you have consumed any foods or products that contain alcohol (mouthwash, cough medicine, cooking wine or vinegar, certain desserts, and others). Antabuse should never be given to a person without his or her knowledge of taking the medicine. Before taking this medicine. Do not take Antabuse if you have consumed alcohol within the past 12 hours. Do not drink alcohol while taking disulfiram and for up to 14 days after you stop taking this medicine. You should not use Antabuse if you are allergic to disulfiram, or if: you have recently taken metronidazole (Flagyl) or paraldehyde; or you have consumed any foods or products that contain alcohol (mouthwash, cough medicine, cooking wine or vinegar, certain desserts, and others). To make sure Antabuse is safe for you, tell your doctor if you have: liver or kidney disease; heart disease, high blood pressure, history of heart attack or stroke; underactive thyroid; diabetes; seizures or epilepsy; head injury or brain damage; a history of mental illness. FDA pregnancy category. It is not known whether Antabuse will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine. See also: antabuse treatment for alcoholism Pregnancy and breastfeeding warnings (in more detail). It is not known whether disulfiram passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine. Do not give this medicine to anyone under 18 years old without medical advice. How should I take Antabuse? Take Antabuse exactly as directed by your doctor.